When Zyban was launched in the UK last June, it was hailed as a wonder drug that could help millions of people stop smoking. Health chiefs today moved to reassure people that the drug was safe. Zyban, known as bupropion hydrochloride, is made by drugs giant GlaxoSmithKline. Bupropion is an antidepressant medication used to treat major depressive disorder and seasonal affective disorder.
The Zyban brand of bupropion is used to help people stop smoking by reducing cravings and other withdrawal effects. This medication is used in combination with a stop-smoking program (e.g., support group, counseling) to help you quit smoking. Bupropion can decrease your nicotine withdrawal symptoms and your urge to smoke. Take this medication by mouth, usually twice daily with or without food. If stomach upset occurs, take with food. It is important to take your doses at least 8 hours apart or as directed by your doctor to decrease your risk of seizure.
You may have trouble sleeping when you start taking this drug. Do not take your evening dose too close to bedtime. Do not crush or chew this medication. Doing so can release the entire drug at once, increasing the risk of side effects, including seizures. Your dosage is based on your medical condition and response to therapy. Your dose may be slowly increased to limit side effects. Do not take more or less medication than prescribed. Dosing Bupropion usually is given in one, two or three daily doses. For immediate-release tablets, no single dose should exceed 150 mg and each dose should be separated by 6 hours. Maximum dose is 450 mg daily. The initial dose is 100 mg twice daily. The dose may be increased to 100 mg 3 times daily after three days. The initial dose of sustained-release tablets is 150 mg daily; target dose is 150 mg twice daily; maximum dose is 200 mg twice daily.
Bupropion is used to treat depression. It can improve your mood and feelings of well-being. It may work by helping to restore the balance of certain natural chemicals in your brain. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.
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